A translational research lab at Temple University.
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JOHN ELROD, PhD
John is an Associate Professor in the Center for Translational Medicine at the Lewis Katz School of Medicine at Temple University. John received his Ph.D. from the Albert Einstein College of Medicine where he published seminal work on the cytoprotective mechanisms of hydrogen sulfide in the lab of Dr. David Lefer. He then trained in molecular biology under Howard Hughes Investigator, Dr. Jeff Molkentin, at Cincinnati Children's Hospital as an NIH-funded postdoctoral fellow. In Cincinnati, John published work detailing a physiological function for the mitochondrial permeability transition pore. During his fellowship he was central in establishing a high-throughput screening facility and also developed new mutant mouse models to study the mitochondrial calcium microdomain. His current research is focused on understanding the molecular regulation of mitochondrial calcium exchange in disease and he continues to search for new genes and pathways involved in necrotic cell death with a therapeutic focus on myocardial infarction and heart failure.
POOJA JADIYA, PhD
Pooja received her Ph.D. in Life Sciences from CSIR-Central Drug Research Institute in Lucknow, India. Pooja’s doctoral work focused on functional genomics and epigenetic alterations in a C. elegans neurodegenerative disease model. Her current research is focused on discovering novel molecular regulators of mitochondrial calcium signaling and how they may impact chronic diseases such as as neurodegeneration.
1st place poster award, 4th Annual Temple Translational Science Symposium
1st place poster award, 6th Regional Translational Research in Mitochondrial, Aging, and Disease (TriMAD) Symposium
Committee for Professional Opportunities for Women Travel Award from Biophysical Society
Poster Award (2nd place) at Mid-Atlantic Pharmacology Society (MAPS), Symposium
The Eliot Stellar Award (1st place), Annual Meeting of the Philadelphia Chapter of the Society for Neuroscience
JOANNE GARBINCIUS, PhD
Joanne received her B.A. in Biological Sciences from Cornell University and completed her Ph.D. in Molecular & Integrative Physiology at the University of Michigan. Her thesis research, under the mentorship of Professor Daniel E. Michele, investigated mechano-sensitive signaling by the dystrophin-glycoprotein complex and its relevance to heart and skeletal muscle dysfunction in muscular dystrophies. Joanne’s current interests include the physiological role of mitochondrial flux in responses to cardiac stress and the molecular regulation of mitochondrial calcium efflux.
ANDREW GIBB, PhD
Andrew received his Ph.D. from the University of Louisville under the mentorship of Dr. Brad Hill. His graduate work was the first to show that metabolic changes elicited by acute exercise are required for physiologic cardiac growth. Andrew joined the Elrod lab in January of 2018 and is currently investigating the interplay of metabolism and epigenetics in the context of cardiac health and disease.
DHANENDRA TOMAR, PhD
Dhanendra received his Ph.D. in Cell Biology from the University of Pune in India. His thesis studies focused on the role of TRIM family of ubiquitin E3 ligases in autophagy and NF-kB signaling. He also worked at the University of Bordeaux in France as a visiting scholar where he studied the role of ubiquitination in mitochondrial biology. His initial postdoctoral research was focused on the molecular mechanism of mitochondrial calcium exchange. Currently, he is examining the molecular determinants of mitochondrial dynamics and resultant physiology. Besides reading the scientific literature, DT enjoys reading history books, watching documentaries, traveling, cycling, and kayaking.
New Investigator Travel Award, BCVS 2018
ALYSSA LOMBARDI, PhD
Alyssa received her B.S. in biology from Lehigh University. She was a research assistant for 3 years at the University of Pennslyvania where she studied stability mechanisms of the beta-globin gene in the lab of Dr. Eric Russell.
Alyssa successfully defended her thesis titled: “MITOCHONDRIAL CALCIUM EXCHANGE LINKS METABOLISM WITH THE EPIGENOME TO CONTROL CELLULAR DIFFERENTIATION” in April of 2018 and is continuing to work in the lab during her 3rd and 4th year of medical school.
When she is not studying or in the lab, she likes to spend time at the beach in her hometown of Ocean City, NJ.
JONATHAN LAMBERT, BS
Jonathan joined the Biomedical Sciences Program at Temple University School of Medicine in 2014. He is an alum of Boston College with a B.S. in Biology. After graduating he joined the laboratory of Dr. John Calvert at Emory University School of Medicine as a research technician. At Emory he primarily studied the cardioprotective effects of hydrogen sulfide, a gaseous signaling molecule, in the setting of heart failure. His current work is focused on the molecular regulation of the mitochondrial calcium uniporter.
Emma received her B.S. in bioinformatics from Ramapo College of New Jersey. There she preformed computational based research on the regulation of G-quadruplexes in neurological disorders. Currently, she is developing discovery-based approaches (in silico and in vitro) to identify new genes that may play prominent role in cardiac physiology and disease with a focus on identifying new regulators of cell death.
Pre-doctoral Fellowship (F31), NIH-NHLBI 2018
ALYCIA HILDEBRAND, BS
Research Technician and Animal Surgeon
Alycia received her B.S. from Ursinus College in Mathematics with a minor in Biology. During her time at Ursinus, Alycia studied the effects of Wnt pathway activation on inflammation and endothelial permeability in the SkM Lab with Dr. April Carpenter. Her primary role in the lab is serving as the assistant director and surgeon for our PPG funded surgical core to study IR-injury and heart failure and also assists with maintenance of our large murine colony.
TREVOR TIERNEY, BS
After graduating from Temple University in 2009 Trevor spent two years as an assistant zookeeper at the Philadelphia Zoo, which led him to the jungles of Costa Rica to gain experience in exotic animal rehabilitation and veterinary care. Upon returning to the United States Trevor began a five-year stint in the Smilow Center for Translational Research at the University of Pennsylvania as an animal care specialist and research assistant, eventually joining the ULAR department in an administrative role. Trevor now manages the daily activities of the Lab and our large mutant mouse colony.
DEVIN KOLMETZKY, BS
Devin joined the lab as a freshman in 2014 and has become an integral member of over the last four years. He graduated from Temple University’s Honors Program in the spring of 2018 and is currently applying to MD/PhD programs . Devin is the lab's histology expert and virus production specialist. His research interests include brain injury and neurodegeneration.
NEIL SHAH, BS
Neil Shah is a Presidential Scholar at Temple University majoring in biochemistry under the pre-med track . Neil started as a summer intern and has since became an integral member of the lab, contributing to multiple projects. Neil's long-term goal is to become an academic research scientist/clinician. Neil will be attending Rutger’s Medical School in the fall.
PAST LAB MEMBERS
Neil Shah, BS Rutgers Medical School
Tim Luongo, PhD University of Pennsylvania - Postdoctoral Fellow
Anita Mehta, MD Cooper University Hospital - Internal Medicine
Esther Kim, MD Resident Dept. of Pediatrics, UCLA School of Medicine
Mary Nwokedi Howard University - Pharm.D. Program
Ehtesham Arif, PhD Medical University of South Carolina - Staff Scientist