Temple hosted it's 6th Annual Temple Translational Science Symposium. Pooja, Jonathan, Alyssa and Emma all presented their work. Alyssa won the Travel Award for her presentation on mitochondrial bioenergetic signaling in myofibroblast differentiation. Congratulations Alyssa!
The CTM gathered to celebrate Dr. Kishore's new NHLBI PPG grant focused on exosome therapy. Congratulations to Dr. Kishore and the rest of the Temple team.
CTM trainees went out to Luke's Lobster for lunch to celebrate Nora's last day. Congrats to Nora on her new teaching position in Italy!
Jörg Heineke - Professor at Hannover Medical School and Molkentin alum, gave an excellent talk as part of the CTM Seminar Series on the Molecular Mechanisms of Heart Failure.
Dr. Elrod and lab members Jonathan and Alyssa attended the AHA-BCVS conference in Portland, Oregon. Dr. Elrod participated as a judge for the New Investigator Award competition and as a panel member of a special session. Alyssa presented two abstracts, one on myofibroblast transdifferentiation and a second on a novel necrotic cell death pathway, and Jonathan presented his work on MCUB regulation of mitochondrial calcium uptake.
Temple's Lewis Katz School of Medicine held its 16th Annual Dawn Mark's Day student research showcase. This years event featured 44 student poster exhibits and 10 oral presentations. Jonathan gave an oral presentation on MCUb regulation of mitochondrial calcium uptake and Alyssa presented on new mechanisms of myofibroblast differentiation and won second place in the poster competition. Congratulations Alyssa!
After a year of revisions the NCLX paper was finally accepted at Nature. The focus of the work was defining the contribution of the mitochondrial sodium/calcium exchanger in cardiac physiology and disease. Congrats to Tim!
The article can be found here.
The lab ended 2016 with the annual CTM-CVRC karaoke blowout. Tim was hard at work with his selfie stick.
John, Alyssa, Tim and Jonathan attended the Experimental Biology Conference in San Diego, California. Alyssa presented her work on mechanisms of myofibroblast differentiation; Jonathan presented his wok on MCUB regulation of mitochondrial calcium uptake; Tim presented his work on the role of NCLX in heart failure. Tim and Alyssa were both awarded the APS Cardiovascular Research Recognition Award for their top scoring abstracts. Congratulations Tim and Alyssa!
The lab attend the Biophysical Society Conference in New Orleans, Lousiana. Pooja presented her work on mitochondrial calcium efflux in AD and won the Committee for Professional Opportunities for Women (CPOW) Travel Award. Alyssa presented her work on myofibroblast transdifferentiation in myocardial infarction and won the Biophysical Society Education Travel Award. Congratulations Pooja and Alyssa!
The Lab attended Scientific Sessions in Orlando and had a great time. The highlight was Fede Accornero (former Molkentin trainee) winning the Katz Basic Science Research Prize. By chance, three former Lefer trainees were all featured in the same session 'Cardiac Cell Death - Prevention and Recovery'.
I was lucky to travel to Israel to visit my good friend Izhak Kehat in Haifa and give a talk at Technion. The highlight of the trip was the personal tour by Izhak to various religious landmarks in the North of Israel. From there it was onto Jerusalem for the 7th International Conference on Sodium Calcium Exchange thanks to a lecture invite from our friend and collaborator, Israel Sekler. Beyond the great science presented at this meeting, I had the intense experience of spending significant time touring Jerusalem.
Tim Luongo (PhD candidate) won the New Investigator Travel Award and was the top scoring abstract out of over 400 submitted for his work titled: "Genetic Deletion of Slc8b1, the mitochondrial sodium/calcium exchanger, causes sudden death and overexpression protects against MI and pressure-overload heart failure." John gave a talk in a session featuring mitochondrial biology in cardiovascular disease.
Our own Dr. Steve Houser was named President of the American Heart Association. Congrats Steve!
The lab finally got its first research article published in Cell Reports. The focus of the work was defining the contribution of MCU-mediated calcium uptake to cardiac physiology and disease. Congrats to Tim on his first paper! The work was also picked up by a couple news outlets.
Tim Luongo, PhD student in the lab, won 1st place poster in the Temple/Fox Chase Research Symposium, which features work by all the graduate students. Congrats Tim, way to represent!
Had an excellent time interacting with some of the top 'Greek' scientists from around the world. This school, founded by my colleague, Dr. Costas Drosatos, is truly an amazing event. I had the privilege of giving a couple lectures and interacting with numerous trainees from around the world. I made some life long friends on this trip and also had the privilege of spending some time with the Godfather of Molecular Cloning, Tom Maniatis. AND it also happens to take place in Mani, Greece.......
Dr. Elrod and Tim Luongo traveled to the AHA Scientific Sessions meeting in Chicago. Tim presented a poster entitled, "Cardiomyocyte Overexpression of the Mitochondrial Sodium/Calcium Exchanger (mitoNCX) Increases Matrix Calcium Efflux and Preserves Cardiac Function in Mouse Models of Heart Failure." Tim got a lot of great feedback and had a great time.